Humidity control device
Raman spectrum measurements are possible under humidity conditions.
The stability testing guidelines state that stability tests, which determine the shelf life of formulations and storage conditions for pharmaceuticals under various environmental factors such as temperature, humidity, and light, are necessary tests for drug approval applications. Therefore, using Raman spectroscopy, which allows for non-contact measurements and is used for identifying polymorphs similar to powder X-ray diffraction, we focused on one of the environmental factors, "humidity," and analyzed and evaluated the crystal transition from hydrate to anhydrous form of caffeine under humidification conditions of a model formulation using Raman spectra, demonstrating that Raman spectroscopy is effective for observing the crystal form of active pharmaceutical ingredients under humidification conditions.
- Company：テックアナリシス
- Price：Other
